Polynucleotide Skin Treatment

At CB Aesthetics & Medical, we believe true luxury in aesthetics lies in restoration - not alteration.
Polynucleotide therapy is an advanced regenerative treatment designed to repair, strengthen and revitalise the skin at a cellular level.
Subtle yet transformative, this treatment enhances your skin's natural architecture, restoring luminosity, firmness and refined texture without adding volume or altering facial contours.
This is regenerative aesthetics at its most sophisticated.
What Are Polynucleotides?
Polynucleotides are highly purified DNA-derived molecules that stimulate deep dermal repair. Once precisely administered, they activate fibroblasts, encourage collagen and elastin synthesis, improve microcirculation and restore optimal hydration.
The result is skin that appears smoother, firmer, brighter and unmistakably healthy.
Unlike traditional injectables, polynucleotide skin treatments do not “fill” — they regenerate.


Indications
This treatment is ideal for patients seeking refined, natural rejuvenation, including:
- Delicate under-eye rejuvenation
- Crepey or thinning skin
- Early to moderate skin laxity
- Dull or fatigued complexion
- Acne scarring
- Sun-damaged skin
- Neck and décolletage ageing
- Hand rejuvenation
Suitable for both preventative and corrective treatments.
Treatment Areas & Investment
We offer premium, medically-led polynucleotide skin treatments using industry-leading formulations.
Under Eye Rejuvenation
From £275
Full Face Regeneration
From £375
Neck Rejuvenation
From £325
Décolletage
From £350
Hands
From £325
Targeted Acne Scarring
From £275
Stretch Marks
(Small Area)
From £300
A bespoke polynucleotide skin treatment plan will be created following your consultation.
Polynucleotide Treatment Frequently Asked Questions
When Will I See Results?
Polynucleotide skin treatment works progressively: • Improved hydration: 1–2 weeks • Firmer, smoother skin: 4–6 weeks • Continued collagen stimulation: up to 12 weeks Results appear natural, refreshed and refined.
Who Is Suitable for Polynucleotide Skin Rejuvenation?
This treatment is ideal if you: • Have tired, dull or ageing skin • Notice under-eye crepiness or dark circles • Want non-surgical skin tightening • Prefer regenerative treatments over fillers • Have acne scarring or sun damage • Want preventative anti-ageing treatment
Are polynucleotides better than fillers?
Polynucleotides do not add volume like dermal fillers. Instead, they improve skin quality, elasticity and collagen production, making them ideal for natural rejuvenation.
Do polynucleotide injections hurt?
Discomfort is minimal. Numbing cream can be applied to ensure comfort during treatment.
Is there downtime after polynucleotide treatment?
Downtime is minimal. Mild swelling or redness typically resolves within 24–48 hours.
How long do polynucleotide results last?
Results can last 6–9 months following a full course of treatment, depending on skin condition and lifestyle factors.
Are polynucleotides safe?
Yes. When administered by trained medical professionals, polynucleotide injections are safe and clinically proven for skin regeneration.
Our Location
We offer injectable treatments at our clinic in Blewbury, Oxfordshire. We are in very close proximity to Oxford, Aylesbury, Reading, Newbury, Swindon, Wiltshire, High Wycombe, Maidenhead and Berkshire.
Contact us at CB Aesthetics to book a free no obligation consultation.

